Protein Sequence and Structure: Is One More Fundamental than the Other?
نویسندگان
چکیده
منابع مشابه
Protein sequence and structure: Is one more fundamental than the other?
We argue that protein native state structures reside in a novel “phase” of matter which confers on proteins their many amazing characteristics. This phase arises from the common features of all globular proteins and is characterized by a sequence-independent free energy landscape with relatively few low energy minima with funnel-like character. The choice of a sequence that fits well into one o...
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ژورنال
عنوان ژورنال: Journal of Statistical Physics
سال: 2012
ISSN: 0022-4715,1572-9613
DOI: 10.1007/s10955-012-0456-3